Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease

Stopped early · Phase 2 · Has a placebo group

Conditions studied: Alzheimer's Disease

In brief

The purpose of this study is to test if the investigational medication ABT-089 is a safe and effective treatment for Alzheimer's disease.

Key facts

Study ID

NCT00555204

Run by

Abbott

People needed

337

Starts

2007-11-01

Last updated by the study team

2011-08-23

Who can join

Age: 55 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient has mild to moderate Alzheimer's disease
• Patient has been receiving a stable dose of an acetylcholinesterase inhibitor
• Patient has a MMSE score between 12 and 26
• Patient has a MHIS score of less than or equal to 4
• Females must be postmenopausal for at least two years or surgically sterile
• Patient has an identified, reliable, caregiver who will support him/her to ensure compliance with treatment and will accompany them to each outpatient visit

You may not qualify if…

• Patient is living in a nursing home
• Patient has a history of any significant neurologic disease other than Alzheimer's disease
• Patient has any uncontrolled medical illness
• Patient uses non-prescribed drugs of abuse or has a history of drug or alcohol abuse/dependence

Where it is running

• Study site — Phoenix, Arizona, United States
• Study site — Sun City, Arizona, United States
• Study site — Fresno, California, United States
• Study site — San Diego, California, United States
• Study site — Santa Ana, California, United States
• Study site — Santa Monica, California, United States
• Study site — Hamden, Connecticut, United States
• Study site — New Haven, Connecticut, United States
• Study site — Brooksville, Florida, United States
• Study site — Delray Beach, Florida, United States
• Study site — Fort Myers, Florida, United States
• Study site — Hallendale, Florida, United States
• Study site — Hialeah, Florida, United States
• Study site — Largo, Florida, United States
• Study site — Miami, Florida, United States
• Study site — Palm Beach Gardens, Florida, United States
• Study site — Sunrise, Florida, United States
• Study site — Tampa, Florida, United States
• Study site — West Palm Beach, Florida, United States
• Study site — West Palm Beach, Florida, United States
• Study site — Indianapolis, Indiana, United States
• Study site — Paducah, Kentucky, United States
• Study site — Pittsfield, Massachusetts, United States
• Study site — Grand Rapids, Michigan, United States
• Study site — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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