G-CSF and Pegfilgrastim in Treating Neutropenia in Patients Undergoing Radiation Therapy and Chemotherapy for Limited Stage Small Cell Lung Cancer
Completed · Phase 2
Conditions studied: Lung Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Colony-stimulating factors, such as G-CSF or pegfilgrastim, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy and radiation therapy. PURPOSE: This phase II trial is studying G-CSF and pegfilgrastim to see how well they work in treating neutropenia in patients undergoing combination chemotherapy and radiation therapy for limited stage small cell lung cancer.
Key facts
- Study ID
- NCT00554463
- Run by
- Radiation Therapy Oncology Group
- People needed
- 5
- Starts
- 2008-01-01
- Expected to finish
- 2011-08-03
- Last updated by the study team
- 2019-05-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Florida Shands Cancer Center — Gainesville, Florida, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- Lucille P. Markey Cancer Center at University of Kentucky — Lexington, Kentucky, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Northern Rockies Radiation Oncology Center — Billings, Montana, United States
- Methodist Estabrook Cancer Center — Omaha, Nebraska, United States
- McDowell Cancer Center at Akron General Medical Center — Akron, Ohio, United States
- Summa Center for Cancer Care at Akron City Hospital — Akron, Ohio, United States
- Charles M. Barrett Cancer Center at University Hospital — Cincinnati, Ohio, United States
- Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
- Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford — Salem, Ohio, United States
- Cancer Treatment Center — Wooster, Ohio, United States
- McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center — Reading, Pennsylvania, United States
- Veterans Affairs Medical Center - Milwaukee — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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