Effect of Cranberry Juice on Endothelial Function
Completed · Not applicable
Conditions studied: Coronary Artery Disease
In brief
A pilot study of 15 subjects will be completed to determine whether acute consumption of cranberry juice has an effect on endothelial function. We will then complete a randomized, double blind, placebo controlled crossover study designed to investigate the effects of cranberry juice consumption on endothelial function. Participants (n=40) will drink 480 ml of double strength cranberry juice or a similar appearing and tasting placebo per day for four weeks. After a two week rest period, they will cross over to the other beverage. We will examine endothelial function before and after each of the two treatment periods. The study will provide information about the chronic vascular effects of cranberry juice.
Key facts
- Study ID
- NCT00553904
- Run by
- Boston University
- People needed
- 40
- Starts
- 2008-02-01
- Expected to finish
- 2009-05-01
- Last updated by the study team
- 2009-06-18
Who can join
Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Coronary artery disease
You may not qualify if…
- Pregnant and lactating women
- Clinical history of other major illness including end-stage cancer, renal failure, hepatic failure, gastrointestinal disorders that may impair absorption, or other conditions that in the opinion of the principal investigator make a clinical study inappropriate
- Treatment with an investigational new drug within the last 30 days
- History of a psychological illness or condition such as to interfere with the subject's ability to understand the requirements of the study.
- Treatment with Vitamin E, Vitamin C, beta carotene, lipoic acid, or other food or herbal supplements within 2 weeks of enrollment (subjects taking multivitamins or other forms of vitamin E and C in doses that do not exceed two times the RDA will not be excluded).
Where it is running
- Boston Medical Center — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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