The Immune Function Intervention Trial

Completed · Not applicable

Conditions studied: Immune Response

In brief

The purpose of the study is to examine whether cardiovascular exercise training improves immune responses to vaccination in previously sedentary older adults.

Key facts

Study ID

NCT00548990

Run by

National Institute on Aging (NIA)

People needed

150

Starts

2002-08-01

Expected to finish

2006-07-01

Last updated by the study team

2009-01-27

Who can join

Age: 62 and older, up to 82. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Ages 62-82
• Ability to participate in an exercise program
• Medical clearance by primary physician
• Non-smoker
• BMI 22-38
• Independently living
• Post-menopausal
• Sedentary for over 6 months

You may not qualify if…

• No recent history (within 6 months) of infection or vaccination
• History of systemic reactions to vaccination
• History of cancer
• Severe allergies/asthma requiring prescription medication
• Splenectomy or transplant patient
• Chronic Obstructive Pulmonary Disease (COPD)
• HIV positive
• Uncontrolled diabetes or hypertension
• Severe arthritis
• Mental illness or clinical depression
• Impaired cognitive status

Where it is running

• University of Illinois at Urbana-Champaign — Urbana, Illinois, United States

Full record on ClinicalTrials.gov

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