The Active After Cancer Trial (AACT)

Running, not enrolling · Not applicable

Conditions studied: Breast Cancer, Colorectal Cancer

In brief

This study is being done to determine whether a telephone-based counseling intervention can help survivors of breast and colorectal cancer increase their weekly physical activity. Observational evidence suggests that physical activity after breast and colorectal cancer diagnosis decreases recurrence rates. Unfortunately, many people become less active during cancer therapy, and a substantial proportion never return to pre-diagnosis levels of physical activity. This study looks to see if people who have recently finished chemotherapy for breast, colon or rectal cancer can be motivated to increase their exercise by talking to an exercise specialist over the phone. The study also looks at changes in mood, fatigue, fitness, fat distribution and weight.

Key facts

Study ID

NCT00548236

Run by

Dana-Farber Cancer Institute

People needed

120

Starts

2007-10-01

Expected to finish

2026-12-01

Last updated by the study team

2026-02-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically confirmed stage I-III breast or colorectal cancer
• 18 years of age or older
• Completed adjuvant treatment(for current malignancy)
• Completion of all adjuvant chemotherapy and radiation (with the exception of adjuvant herceptin and/or tamoxifen/aromatase inhibitor therapy for breast cancer patients) between 2 and 36 months prior to enrollment
• Ability to speak and read English
• Willingness to be randomized
• Medical clearance from an oncologist or primary care physician stating the participant is able to participate in an unsupervised, moderate-intensity physical activity program
• No major surgery within 2 months of study enrollment or planned during study period

You may not qualify if…

• Metastatic cancer
• Uncontrolled intercurrent illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness that would limit compliance with study requirements
• Plans to have hip or knee replacement within a year
• Participation in more than 60 minutes a week of moderate-intensity recreational activity as assessed by the International Physical Activity Questionnaire Short Form
• BMI >47

Where it is running

• University of California at San Diego — La Jolla, California, United States
• University of California San Francisco — San Francisco, California, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• New Hampshire Oncology Hematology — Concord, New Hampshire, United States
• Lakes Regional Healthcare Hematology Oncology — Hooksett, New Hampshire, United States
• Rosewell Park Cancer Institute — Buffalo, New York, United States
• Hematology Oncology Associates of Central New York — East Syracuse, New York, United States
• Ohio State University — Columbus, Ohio, United States
• Vermont Cancer Center — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.