PET Imaging of Peripheral Benzodiazepine Receptors in Patients With Carotid Atherosclerosis

Completed · Phase 1

Conditions studied: Atherosclerosis, Healthy

In brief

Inflammation in the vascular wall is important in atherosclerosis and the blockage of the artery. The peripheral benzodiazepine receptor is involved in inflammation and in this protocol we will attempt to take pictures, using PET camera, of inflammation in patients with atherosclerosis and compare those of healthy people.

Key facts

Study ID

NCT00547976

Run by

National Institute of Mental Health (NIMH)

People needed

5

Starts

2007-10-01

Expected to finish

2009-08-01

Last updated by the study team

2012-04-27

Who can join

Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Severe systemic disease based on history, physical examination or laboratory tests that would prevent participation in the study
• Prior participation in other research protocols in the last year such that radiation exposure would exceed the annual guideline of RSC
• Pregnancy and breast feeding
• Claustrophobia
• Inability to lie flat for a few hours for the PET scans
• Medically unstable
• The blood glucose level is greater than 150 mg/dL after fasting
• Any other condition which in the opinion of the PI would prevent satisfactory participation in and completion of the study.

Where it is running

• Suburban Hospital — Bethesda, Maryland, United States
• National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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