Home-Based Assessment for Alzheimer Disease Prevention

Completed · Not applicable

Conditions studied: Mild Cognitive Impairment, Alzheimer's Disease

In brief

The purpose of this study is to evaluate three methods of performing home-based assessments in Alzheimer's Disease (AD) prevention trials. The initial in-person assessment will be done in the clinic or at home.

Key facts

Study ID

NCT00546767

Run by

Alzheimer's Disease Cooperative Study (ADCS)

People needed

640

Starts

2007-09-01

Expected to finish

2013-06-01

Last updated by the study team

2014-09-16

Who can join

Age: 75 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 75 and older
• Willing to sign consent
• Willing to take multi-vitamins provided by the study
• Minimal computer skills or willingness to learn (as demonstrated by completion during screening of a demonstration module for each arm)
• English fluency
• MMSE greater than 26
• Able to answer and dial a telephone
• Able to complete the in-person assessment
• Able to complete the computerized assessment including adequate speech, hearing and vision
• Independently living adults, defined as living in a setting in which the participant can ensure access to the resources for study procedures
• Participation of a study partner is desirable and encouraged, but not required

You may not qualify if…

• Dementia
• Use of prescription cognitive-enhancing drugs at entry (e.g. Aricept, Razadyne, Exelon, Namenda)
• Intent to continue use of own multi-vitamins (for the duration of the study participants must agree to take only study-distributed multi-vitamins)
• History or presence of major psychiatric, neurological or neurodegenerative conditions associated with significant cognitive impairment such as major stroke, Parkinson's disease, Multiple Sclerosis or Huntington's disease. Transient Ischemic Attack (TIA) is acceptable if over 6 months ago
• Medical conditions associated with life expectancy of less than 5 years
• Transient domicile interfering with ability to collect study-related data
• Current participation in a clinical trial involving Central Nervous System (CNS) medications or cognitive testing that would interfere with the current protocol (participation in Uniform Data Set (UDS) assessments by an ADC is permitted)
• Cohabitation with another participant in this particular study

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Sun Health Reseach Institute — Sun City, Arizona, United States
• University of California, Irvine Institute for Brain Aging and Dementia — Irvine, California, United States
• University of California-San Diego ADRC/Neurosciences — La Jolla, California, United States
• University of California, Davis — Martinez, California, United States
• Stanford University / PAIRE — Palo Alto, California, United States
• Yale University Alzheimer's Disease Research Unit — New Haven, Connecticut, United States
• Georgetown University — Washington D.C., District of Columbia, United States
• Mayo Clinic Jacksonville Neurology — Jacksonville, Florida, United States
• Wien Center — Miami Beach, Florida, United States
• University of South Florida, Suncoast Alzheimer's & Gerontology Center — Tampa, Florida, United States
• Northwestern University Cognitive Neurology & Alzheimer's Disease — Chicago, Illinois, United States
• Rush Alzheimer's Disease Center — Chicago, Illinois, United States
• Indiana University — Indianapolis, Indiana, United States
• University of Kentucky Sanders-Brown Center on Aging — Lexington, Kentucky, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• Boston University Alzheimer's Disease Clinical and Research Program — Boston, Massachusetts, United States
• University of Michigan Psychiatry - Neuropsychology — Ann Arbor, Michigan, United States
• University of Nevada School of Medicine — Las Vegas, Nevada, United States
• New York University Aging and Dementia Research Center — New York, New York, United States
• Mount Sinai School of Medicine — New York, New York, United States
• Neurological Care of CNY — Syracuse, New York, United States
• Wake Forest University Gerontology and Geriatric Medicine — Winston-Salem, North Carolina, United States
• Case Western Reserve University — Cleveland, Ohio, United States
• The Ohio State University — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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