Zalutumumab in Non-curable Patients With SCCHN

Completed · Phase 2

Conditions studied: Head and Neck Cancer, Squamous Cell Cancer

In brief

Treatment, In combination with BSC, Open-label, Single arm, Efficacy Study.

Key facts

Study ID

NCT00542308

Run by

Genmab

People needed

90

Starts

2008-01-01

Expected to finish

2011-08-01

Last updated by the study team

2023-08-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Males and females age ≥ 18 years
• Confirmed diagnosis, initially or at relapse, of squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx or larynx, considered incurable with standard therapy
• Failure to at least one course of standard platinum-based chemotherapy

You may not qualify if…

• Three or more prior chemotherapy regimens
• Prior treatment with EGFr antibodies and/or EGFr small molecule inhibitors
• Past or current malignancy other than SCCHN, except for certain other cancer diseases

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Loma Linda University Cancer Institute — Loma Linda, California, United States
• Moffitt Cancer Center — Tampa, Florida, United States
• Mountain States Tumor Institute — Boise, Idaho, United States
• University Of Chicago Medical Center — Chicago, Illinois, United States
• Ft. Wayne Medical Oncology/Hematology, Inc — Fort Wayne, Indiana, United States
• Henry Ford Health Systems — Detroit, Michigan, United States
• Oregon Health and Science University — Portland, Oregon, United States
• Baylor University Medical Center — Dallas, Texas, United States
• Medizinische Universität Graz — Graz, Austria
• Universitätsklinik für Innere Medizin III — Salzburg, Austria
• AKH Wien — Vienna, Austria
• Instituto Clinico Oncologico del Sur ICOS — Temuco, Chile
• Hospital Carlos Van Buren de Valparaiso — Valparaíso, Chile
• Instituto Oncologico — Viña del Mar, Chile
• Centro de Investigaciones Oncologicas Clinica CIO San Diego S.A — Bogotá, Colombia
• Hospital Pablo Tobon Uribe — Medellín, Colombia
• Oncomedica S.A. — Montería, Colombia
• Oncólogos del Occidente S.A. — Pereira, Colombia
• Facultni Nemocnice Hradec Kralove — Hradec Králové, Czechia
• Nemocnice Jihlava — Jihlava, Czechia
• Veseobecna Fakultni Nemocnice — Prague, Czechia
• Facultni Nemocnice Na Bulovce — Prague, Czechia
• Universitätsklinikum Essen — Essen, Germany
• Klinikum der Johann Wolfgang Goethe Universität — Frankfurt am Main, Germany

Full record on ClinicalTrials.gov

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