Prevention of Narcotic-Induced Nausea

Stopped early · Not applicable

Conditions studied: Nausea

In brief

We are doing this study to find out if extra medicine is needed to avoid the chance of nausea sometimes linked to narcotic pain medicine (for example, morphine, dilaudid, fentanyl). Some doctors always give medicine to prevent the possible side effect of nausea, while others do not. We are looking to see if this extra medicine is helpful in preventing nausea. The goal is to screen all patients with pain and enroll enough subjects to reach our goal of 164 evaluable study participants.

Key facts

Study ID

NCT00541671

Run by

Christiana Care Health Services

People needed

25

Starts

2007-02-01

Expected to finish

2009-11-01

Last updated by the study team

2014-03-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patient in Christian Care Emergency Department
• Require intravenous narcotics for painful condition
• ≥18 years of age
• Able to visually rate amount of pain and nausea

You may not qualify if…

• Hypersensitivity to promethazine or opioids
• Patient requesting anti-emetic at enrollment
• Narcotic administration in last 6 hours
• Pregnancy or currently breast-feeding
• Known seizure disorder
• Medical Instability

Where it is running

• Christiana Care Health Services — Newark, Delaware, United States

Full record on ClinicalTrials.gov

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