Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Stopped early

Conditions studied: Constipation, Bowel Obstruction, Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer

In brief

RATIONALE: Gathering information about changes in serotonin levels in patients undergoing chemotherapy for ovarian cancer, fallopian tube cancer, or primary peritoneal cancer may help doctors learn more about constipation caused by chemotherapy. PURPOSE: This clinical trial is studying how blood levels of serotonin effect constipation caused by chemotherapy in patients with newly diagnosed ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.

Key facts

Study ID

NCT00536523

Run by

University of Minnesota

People needed

13

Starts

2007-04-01

Expected to finish

2009-12-01

Last updated by the study team

2014-08-22

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Newly diagnosed ovarian, fallopian tube, or primary peritoneal cancer
• Planned to undergo 6 courses of a taxane and platinum-containing regimen

You may not qualify if…

• Ovarian low malignant potential tumor
• History of constipation or irritable bowel syndrome
• History of colorectal cancer
• Prior bowel resection at time of staging/cytoreductive surgery
• Prior abdominal-pelvic radiation
• Prior bowel surgery

Where it is running

• Masonic Cancer Center at University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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