Reducing Depressive Symptoms in Physically Ill Youth
Completed · Not applicable
Conditions studied: Inflammatory Bowel Disease, Depression
In brief
Children and adolescents with inflammatory bowel disease (IBD) have high rates of depressive symptoms and more trouble with daily functioning than those without physical illness. The proposed study will investigate if cognitive behavioral therapy (CBT) is better than supportive therapy (SNDT) in reducing emotional distress and improving functioning in youth ages 9-17 with Crohn's disease or Ulcerative Colitis and depression. This study will also assess the effect of CBT on IBD-related factors such as disease severity, medication adherence, and physical-health related quality of life. Hypothesis \- Individuals who receive CBT will show more improvement than individuals who receive SNDT.
Key facts
- Study ID
- NCT00534911
- Run by
- University of Pittsburgh
- People needed
- 76
- Starts
- 2007-09-01
- Expected to finish
- 2019-12-01
- Last updated by the study team
- 2020-01-07
Who can join
Age: 9 and older, up to 17. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Step 1:
- ages 9 to 17 inclusive
- capable of completing CDI
- meeting diagnostic criteria for CD (the date of diagnosis = date of the first diagnostic test confirming CD)
- absence of mental retardation by history
- having at least one appointment at the GI clinic (this will include patients followed in these clinics as well as those seeking consultation)
- Step 2:
- CDI or CDI-P greater than or equal to 10 at Step 1.
- ages between 9-17 inclusive
- having CD
You may not qualify if…
- history or current episode of bipolar disorder, eating disorder, or psychotic disorder by DSM-IV criteria
- mental retardation by history
- antidepressant medications within one month of assessment
- suicidality with plan or of severity requiring immediate psychiatric hospitalization or significant act involving intentional self-harm (e.g., cutting or overdose, resulting in medical attention)
- unacceptable risk for dangerousness to others as indicated by homicidal (or other violent) ideation, intent or plan or action, or use of illegal weapons
- current pregnancy by history
- substance abuse by history within one month of enrollment other than nicotine dependence
- current treatment with CBT or failure of previous CBT trial for depression judged adequate by at least 12 treatment sessions over a period of less than 1 year conducted by an appropriately trained mental health provider using a manual
- if currently receiving other psychotherapy modalities willingness to suspend treatment for 12-week acute treatment phase of study
Where it is running
- Children's Hospital-Boston — Boston, Massachusetts, United States
- Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States
Full record on ClinicalTrials.gov
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