Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival
Completed
Conditions studied: Heart Transplantation, Kidney Transplantation, Liver Transplantation, Lung Transplantation
In brief
Activity of genes in donor tissues that are involved in inflammation are thought to be involved with early organ dysfunction, increased immune responses in transplant recipients, and organ rejection. The purpose of this study is to determine the relationship between genetic expression in donor and recipient tissue with transplant survival. Participants in this study will have received heart, lung, liver, or kidney transplants.
Key facts
- Study ID
- NCT00531921
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 313
- Starts
- 2007-09-01
- Expected to finish
- 2011-08-01
- Last updated by the study team
- 2013-06-04
Who can join
Age: any, up to 70. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Northwestern Memorial Hospital (kidney and liver) — Chicago, Illinois, United States
- Cornell University Medical College (kidney) — Ithaca, New York, United States
- Columbia University (lung and liver) — New York, New York, United States
- University of Pennsylvania (heart, kidney, liver, lung) — Philadelphia, Pennsylvania, United States
- University of Wisconsin (heart and lung) — Madison, Wisconsin, United States
Full record on ClinicalTrials.gov
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