NYU Ovarian Cancer Early Detection Program Blood and Genetics

Stopped early

Conditions studied: Ovarian Cancer

In brief

Improving current strategies for detection of early stage disease can impact favorably on long-term survival of women with ovarian cancer. To reduce the morbidity and mortality of ovarian cancer, screening for this disease must detect early stage disease rather than advanced stage disease. Thus the challenge for the future is to identify and develop highly sensitive and specific tumor markers that can be applied to population-based screening for the early detection of ovarian cancer.

Key facts

Study ID

NCT00531778

Run by

NYU Langone Health

People needed

890

Starts

2004-06-01

Expected to finish

2010-11-01

Last updated by the study team

2011-01-11

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women enrolled in the NYU Ovarian Cancer Early Detection Program have at least one of the following risk factors:
• A personal history of breast cancer
• One or more first degree relatives (mother, sister, daughter) with ovarian cancer
• Multiple family members with either breast and/or ovarian cancer
• A personal history of a positive BRCA1 or BRCA2 genetic test result
• A close relative with a positive BRCA1 or BRCA2 genetic test result
• A personal history of colon or endometrial cancer with at least two relatives with a Lynch/HNPCC-associated cancer (colorectal, endometrial, small bowel, ureter, or renal pelvis cancer)
• Synchronous or metachronous endometrial and colorectal cancer
• A personal history of a mismatch repair gene mutation (MLH1, MSH2, MSH6 or PMS2)
• A close relative with a mismatch repair gene mutation (MLH1, MSH2, MSH6 or PMS2)
• A personal history of colorectal or endometrial cancer with a mismatch repair defect (ie. Microsatellite instability (MSI) or immunohistochemical loss of expression of MLH1, MSH2, MSH6, or PMS2)
• The use of fertility drugs for more than one year

Where it is running

• NYUCancer Institute Clinical Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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