The Efficacy of EMLA Cream vs. Synera Patch for Pain Reduction During Venipuncture in Children

Completed · Phase 2

Conditions studied: Pain, Needle Phobia

In brief

This study compares the efficacy of the Synera patch with Eutectic Mixture of Local Anesthetics (EMLA) as a topical anesthetic for venipuncture in pediatric patients.

Key facts

Study ID

NCT00530803

Run by

Montefiore Medical Center

People needed

100

Starts

2007-06-01

Expected to finish

2009-01-01

Last updated by the study team

2018-08-31

Who can join

Age: 4 and older, up to 12. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children in outpatient clinics requiring venipuncture for medical care
• Ages 4-12 years old
• The ability to demonstrate proper understanding of the Wong-Baker FACES Pain Ranking Scale
• Parents of enrolled children need to be present during the procedure and be willing to rate their child's pain

You may not qualify if…

• Damaged or inflamed skin at the designated application site
• Known sensitivity to components of Synera or EMLA (lidocaine, tetracaine, or local anesthetics of the amide or ester type, Para Aminobenzoic (PABA) derivatives)
• Contraindications to SYnera or EMLA use (Severe hepatic disease, history of drug-induced methemoglobinemia, taking Class 1 antiarrhythmics)
• Use of analgesics during the past 24 hours

Where it is running

• Children's Hospital at Montefiore — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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