Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis

Completed · Phase 3 · Has a placebo group

Conditions studied: Adult Periodontitis

In brief

Periodontal disease (commonly called gum disease) is generally treated by deep cleaning of the root surfaces of the teeth. This is also called scaling and root planing. Placing a topical antibiotic into the periodontal pocket at the time of scaling and root planing may help reduce pocket depth and thus help the periodontal disease. Periocline (minocycline HCl) 2.1% gel is a topical antibiotic approved in a number of countries for this use, and is now being tested in the US.

Key facts

Study ID

NCT00529555

Run by

Sunstar Americas

People needed

602

Starts

2006-01-01

Expected to finish

2008-12-01

Last updated by the study team

2014-05-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• moderate to severe periodontitis

You may not qualify if…

• recent periodontal therapy
• certain medical or dental conditions
• pregnancy
• allergy to active drug or related drugs

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• University of California - San Francisco — San Francisco, California, United States
• University of Florida — Gainsville, Florida, United States
• University of Maryland - Dental School — Baltimore, Maryland, United States
• Boston University Dental School — Boston, Massachusetts, United States
• University of Michigan Oral Health Research Center — Ann Arbor, Michigan, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• State University of New York at Buffalo, Dental Medicine — Buffalo, New York, United States
• University of Pennsylvania Dental School — Philadelphia, Pennsylvania, United States
• University of Texas Health Science Center at San Antonio — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.