Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy
Completed · Phase 2
Conditions studied: Prostate Cancer
In brief
RATIONALE: Specialized radiation therapy that delivers a high-dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide, goserelin, flutamide, or bicalutamide, may lessen the amount of androgens made by the body. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with androgen suppression and docetaxel after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well giving radiation therapy together with androgen suppression and docetaxel works in treating patients with high risk prostate cancer who have undergone radical prostatectomy.
Key facts
- Study ID
- NCT00528866
- Run by
- Radiation Therapy Oncology Group
- People needed
- 80
- Starts
- 2008-04-01
- Expected to finish
- 2018-05-14
- Last updated by the study team
- 2019-04-24
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Auburn Radiation Oncology — Auburn, California, United States
- Radiation Oncology Centers - Cameron Park — Cameron Park, California, United States
- Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael, California, United States
- Radiation Oncology Center - Roseville — Roseville, California, United States
- Radiological Associates of Sacramento Medical Group, Incorporated — Sacramento, California, United States
- Mercy General Hospital — Sacramento, California, United States
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Solano Radiation Oncology Center — Vacaville, California, United States
- Urology Center of Colorado — Denver, Colorado, United States
- Poudre Valley Radiation Oncology — Fort Collins, Colorado, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- Cancer Institute at St. John's Hospital — Springfield, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- Norton Suburban Hospital — Louisville, Kentucky, United States
- Tulane Cancer Center Office of Clinical Research — Alexandria, Louisiana, United States
- Mary Bird Perkins Cancer Center - Baton Rouge — Baton Rouge, Louisiana, United States
- MBCCOP - LSU Health Sciences Center — New Orleans, Louisiana, United States
- CCOP - Ochsner — New Orleans, Louisiana, United States
- Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Hudner Oncology Center at Saint Anne's Hospital - Fall River — Fall River, Massachusetts, United States
- Josephine Ford Cancer Center at Henry Ford Hospital — Detroit, Michigan, United States
- Fairview Ridges Hospital — Burnsville, Minnesota, United States
- Mercy and Unity Cancer Center at Mercy Hospital — Coon Rapids, Minnesota, United States
- Arizona Oncology Services Foundation — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
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