Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
Completed · Phase 4
Conditions studied: Esophageal Diseases, Gastrointestinal Diseases, Disorder of the Genitourinary System, Gynecologic Diseases, Kidney Diseases, Liver Diseases, Pancreatic Diseases, Prostate Cancer, Spinal Disease
In brief
The purpose of this study is to determine whether the early identification and more precise intervention of operating room (OR) patient fluid administration optimization using arterial pressure-based cardiac output (APCO) yields comparable patient outcome as fluid administration optimization using a global standard care method.
Key facts
- Study ID
- NCT00526331
- Run by
- M.D. Anderson Cancer Center
- People needed
- 49
- Starts
- 2007-08-01
- Expected to finish
- 2008-09-01
- Last updated by the study team
- 2012-01-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient is in hospital for study indicated treatment.
- Patient is able to comply with the study procedure.
- Patient must require an indwelling radial or a femoral artery catheter.
- Patients with an American Society of Anesthesiologists Risk Score >= 3.
- Lee Risk Index >/= 2 (Hypertension and Pre-diabetic metabolic state).
- Patient must be 40 kg or heavier.
- Patient has consented to be in the trial.
- Patient's height and weight can be accurately obtained prior to study start.
- Patient's ability to undergo major surgery with an anticipated blood loss > 500 ml.
You may not qualify if…
- Patients with contraindications for the placement of radial, femoral, or other arterial cannula.
- Patients with contraindications for the placement of central venous cannula.
- Patients being treated with an intra-aortic balloon pump.
- Patients with aortic valve regurgitation.
- Patients with atrial fibrillation.
- Female patients with a known pregnancy confirmed by urine pregnancy test.
- Patient is currently participating in an investigational drug or another device study that has not completed the primary endpoint or that clinically interferes with the study endpoints.
Where it is running
- U.T.M.D. Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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