COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI

Stopped early · Not applicable

Conditions studied: Gastroesophageal Reflux, Chronic Obstructive Pulmonary Disease

In brief

The purpose of this study is to determine which COPD patients have GERD and if COPD patients with GERD treated with high dose lansoprazole for 1 year decreases the frequency of COPD exacerbations compared to the previous year without treatment.

Key facts

Study ID

NCT00523367

Run by

University of Florida

People needed

25

Starts

2007-08-01

Expected to finish

2010-10-01

Last updated by the study team

2013-01-18

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosis of COPD
• forced expiratory volume/forced vital capacity ratio (FEV1/FVC) of < 70% on pulmonary function testing
• age > 40 years
• >20 pack year history of smoking

You may not qualify if…

• presence of the following disorders: respiratory disorders other than COPD, known esophageal disease such as cancer, achalasia, stricture, active peptic ulcer disease, Zollinger-Ellison syndrome, mastocytosis, scleroderma, or current abuse of alcohol defined as greater than three alcoholic drinks per day.

Where it is running

• University of Florida — Jacksonville, Florida, United States

Full record on ClinicalTrials.gov

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