Correlation Salivary Cortisol and Free Serum Cortisol to Total Serum Cortisol in MICU Septic Shock

Completed

Conditions studied: Septic Shock

In brief

The purpose of the study is: * to correlate salivary cortisol to free serum cortisol (as salivary cortisol is considered to be almost complete free cortisol) and, * to correlate free serum cortisol to total serum cortisol levels Both in patients with septic shock (severe sepsis requiring vasopressors). We believe that: * total serum cortisol does not correlate with free serum cortisol in patient with septic shock and, * that salivary cortisol correlates with free serum cortisol and can be used to determine the level of free serum cortisol.

Key facts

Study ID

NCT00523198

Run by

The University of Texas Health Science Center, Houston

People needed

60

Starts

2007-02-01

Expected to finish

2008-10-01

Last updated by the study team

2014-12-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients with septic shock

You may not qualify if…

• Corticosteroid replacement
• Blood in mouth

Where it is running

• The University of Texas- Health Science Center at Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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