Enhancing Recovery After Cardiac Surgery

Completed · Not applicable

Conditions studied: Coronary Artery Disease, Depression

In brief

Patients recovering from coronary artery bypass graft (CABG) surgery have high rates of depression, and depression is associated with higher risk of complications and death. Recent discoveries show that depression involves changes in certain molecules in the blood, which are also involved in progressive coronary artery disease (CAD) and its complications. This study will evaluate the effects of cognitive behavioral therapy (CBT) as a treatment for depression on these biological markers among CABG patients.

Key facts

Study ID

NCT00522717

Run by

University of California, Los Angeles

People needed

808

Starts

2005-07-01

Expected to finish

2010-05-01

Last updated by the study team

2015-12-02

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergone CABG at one of our recruitment sites

You may not qualify if…

• Less than 45 years of age
• Have cognitive impairment or major comorbid psychiatric conditions
• Have autoimmune disorder or malignancy
• Currently smoking

Where it is running

• Long Beach Memorial Medical Center — Long Beach, California, United States
• Cedars-Sinai Medical Center — Los Angeles, California, United States
• Kaiser Permanente Medical Center - Sunset — Los Angeles, California, United States
• Department of Veterans Affairs-Greater Los Angeles Healthcare System, West Los Angeles — Los Angeles, California, United States
• University of California, Los Angeles School of Nursing — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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