Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease

Completed

Conditions studied: Peripheral Vascular Diseases

In brief

Peripheral arterial disease (PAD) is a disease in which fatty build-up, or "plaque," accumulates in the peripheral arteries. People with PAD often experience leg pain while walking due to reduced blood flow to the legs. This study will use magnetic resonance imaging (MRI) techniques to examine how specific features of plaque build-up in the leg arteries affect walking ability, leg strength, and balance in people with PAD.

Key facts

Study ID

NCT00520312

Run by

Northwestern University

People needed

519

Starts

2007-10-01

Expected to finish

2012-01-01

Last updated by the study team

2014-04-09

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• For participants with PAD: lowest leg ankle-brachial index (ABI) less than or equal to 0.999
• For participants in the control group: lowest ABI between 1.00 to 1.30

You may not qualify if…

• Foot amputation, leg amputation, or gangrene
• Recent liver transplantation
• Requires oxygen on ambulation
• End stage renal disease
• Confined to a wheelchair
• Lives in a nursing home
• Low life expectancy
• Mini-Mental Status Exam (MMSE) score of less than 23 out of 30
• Communication difficulty due to language barriers
• Inability to tolerate MRI testing for any reason
• Six-minute walk performance limited primarily by pulmonary disease, legal blindness, or severe lower extremity arthritis

Where it is running

• Northwestern University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.