Identifying Genetic Determinants of Eczema Herpeticum and Other Viral Infections in Individuals With Atopic Dermatitis

Completed

Conditions studied: Atopic Dermatitis

In brief

People with atopic dermatitis (AD), or eczema, are susceptible to skin infections and inflammations. Some individuals with AD develop a condition known as eczema herpeticum (EH) following exposure to the herpes simplex virus (HSV). The purpose of this study is to identify the genetic determinants that lead people with AD to develop EH and similar conditions caused by other viruses.

Key facts

Study ID: NCT00515047
Run by: National Institute of Allergy and Infectious Diseases (NIAID)
People needed: 900
Starts: 2006-05-01
Expected to finish: 2011-01-01
Last updated by the study team: 2014-04-02

Who can join

Age: 1 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Enrollment in ADVN Biomarker Registry Study
Non-Hispanic and only African American or only Caucasian race
Parent or guardian willing to provide informed consent, if necessary

You may not qualify if…

History of any systemic illness, excluding AD
Participation of a first degree relative already enrolled in the genotyping study unless the subject in question fulfills the diagnostic criteria for ADEH+. More information on this criterion can be found in the protocol.

Where it is running

University of California at San Diego — La Jolla, California, United States
National Jewish Health — Denver, Colorado, United States
Children's Memorial Hospital — Chicago, Illinois, United States
Northwestern University — Chicago, Illinois, United States
Children's Hospital Boston — Boston, Massachusetts, United States
University of Rochester Medical Center — Rochester, New York, United States
Oregon Health & Sciences University — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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