Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder

Completed · Phase 2/Phase 3

Conditions studied: Major Depressive Disorder

In brief

The primary objective of the study was to determine the effects of 10-week adjunctive supplementation with 2 doses of LCn-3 fatty acids (fish oil) on cortical functional activity and biochemistry in adolescents with MDD. The primary prediction was that LCn-3 fatty acid supplementation would dose-dependently increase prefrontal cortical functional activation during sustained attention and increase regional biochemical indices of cortical metabolism and integrity concentrations in association with reductions in depressive symptoms.

Key facts

Study ID
NCT00511810
Run by
University of Cincinnati
People needed
20
Starts
2007-08-01
Expected to finish
2011-03-01
Last updated by the study team
2016-05-27

Who can join

Age: 12 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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