Growth Hormone in Children With Juvenile Rheumatoid Arthritis (JRA) and With Crohn's Disease

Stopped early · Phase 2/Phase 3

Conditions studied: Arthritis, Juvenile Rheumatoid, Crohn Disease

In brief

The investigators hypothesize that the anabolic effects of Genotropin (somatropin) will improve the height and weight of children with inflammatory based chronic illness who have failed to grow despite receiving adequate nutrition. The investigators will test the hypothesis by treating 32 chronically ill children (16 JRA and 16 Crohn's) with growth hormone (GH) for 12 months and comparing them to baseline.

Key facts

Study ID

NCT00511329

Run by

Nationwide Children's Hospital

People needed

10

Starts

2007-08-01

Expected to finish

2010-05-01

Last updated by the study team

2018-04-12

Who can join

Age: 5 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Referral for continued poor growth (growth velocity less than the 25th percentile)
• Height less than the 10th percentile
• Weight less than the 10th percentile compared to age and gender- matched normal values.

You may not qualify if…

• Previous diagnosis with diabetes, chronic fevers (temp > 101.5) or chronic bacterial infection
• Previous treatment with GH
• Bone age > 17

Where it is running

• Columbus Children's Hospital — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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