MR Imaging of Knee Osteoarthritis and Acute Knee Injuries

Completed

Conditions studied: Osteoarthritis, Knee

In brief

The purpose of this study is to use better magnetic resonance imaging (MRI) techniques to examine the knee and the bony and soft tissue changes so as to better predict the progression of osteoarthritis and acute knee injuries.

Key facts

Study ID

NCT00504114

Run by

University of California, San Francisco

People needed

139

Starts

2006-08-01

Expected to finish

2013-07-01

Last updated by the study team

2013-12-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy volunteers will have had no previous knee symptoms or surgery
• Patients with mild arthritic symptoms and Kellgren Lawrence score of 2
• Patients with severe arthritic symptoms and Kellgren Lawrence score of 3, or 4
• Patients with acute ACL injury with associated bone contusion and bone edema
• Patients with posttraumatic knee injury or degenerative condition and will have cartilage resurfacing procedures
• Patient is willing to participate in the proposed study as evidenced by providing written informed consent.

You may not qualify if…

• Current use of an investigational drug
• Conditions other than OA which limit lower extremity function and mobility and/or would confound the evaluation of function (e.g., clinically significant spinal disc degeneration, painful or dysfunctional feet, peripheral vascular disease, lumbar radiculopathy or a stroke.)
• Patients with metallic fragments in the eyes, vascular clips, pacemakers, and other contraindications to MRI

Where it is running

• University of California, San Francisco; MR Surbeck Laboratory of Advanced Imaging — San Francisco, California, United States

Full record on ClinicalTrials.gov

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