Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Recruiting now

Conditions studied: Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS), Interstitial Cystitis

In brief

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the next. In this study, we are collecting genetic material and medical information to try to determine if genetic factors play a role in CP/CPPS. We will be collecting DNA (from Blood/Saliva sample) and urine from each participant. Bladder tissue from affected individuals will also be collected. Individuals and families with CP/CPPS will be enrolled. Family members of an individual with CP/CPPS are eligible whether or not they also experience CP/CPPS symptoms.

Key facts

Study ID

NCT00499317

Run by

Boston Children's Hospital

People needed

500

Starts

2007-01-15

Expected to finish

2028-12-31

Last updated by the study team

2026-06-11

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have symptoms for at least 3 months within the preceding 6 months:
• Pain in the pelvic area
• Urinary frequency and/or
• Urinary urgency and/or
• Sexual dysfunction (erectile dysfunction)
• Have CP/CPPS, Interstitial Cystitis (IC), Bladder Pain Syndrome BPS, or Bladder Fasciculation Syndrome (BFS)
• Be willing to provide a blood/saliva, bladder tissue (from previous biopsy) and urine sample
• Agree to complete several brief questionnaires
• Family member of someone with CP/CPPS, BPS, IC or BFS
• Live in the USA or Canada

You may not qualify if…

• Major structural/anatomical urinary tract abnormalities
• Underlying inborn or congenital conditions which affect the urinary tract
• Surgery/chemotherapy in the pelvic area
• Bacterial cause to CP/CPPS or recurrent Urinary tract infections (UTI)
• Traumatic cause to CP/CPPS

Where it is running

• Boston Children's Hospital (BCH) — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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