Maribavir Versus Oral Ganciclovir For The Prevention of Cytomegalovirus (CMV) Disease in Liver Transplant Recipients

Completed · Phase 3

Conditions studied: Cytomegalovirus Infections

In brief

The purpose of this research study is to investigate whether or not oral maribavir is safe and effective compared to oral ganciclovir for preventing CMV disease when administered for up to 14 weeks in patients who have had a liver transplant.

Key facts

Study ID

NCT00497796

Run by

Shire

People needed

307

Starts

2007-07-23

Expected to finish

2009-09-14

Last updated by the study team

2021-06-11

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Orthotopic liver transplant recipient
• Donor CMV seropositive / Recipient CMV seronegative
• Enrolled within 10 days after liver transplant
• Able to swallow tablets

You may not qualify if…

• Multiple organ transplant
• HIV infection
• CMV disease
• Use of other anti-CMV therapy at time of enrollment

Where it is running

• University of California at San Diego — La Jolla, California, United States
• Cedars-Sinai Medical Center — Los Angeles, California, United States
• UCLA Medical Center — Los Angeles, California, United States
• University of California at San Francisco — San Francisco, California, United States
• Stanford University Medical Center — Stanford, California, United States
• University of Colorado Health Sciences Center — Aurora, Colorado, United States
• Georgetown University — Washington D.C., District of Columbia, United States
• Mayo Clinic College of Medicine — Jacksonville, Florida, United States
• Tampa General — Tampa, Florida, United States
• Emory University — Atlanta, Georgia, United States
• Northwestern University Medical Center — Chicago, Illinois, United States
• Rush University Medical Center — Chicago, Illinois, United States
• University of Illinois at Chicago — Chicago, Illinois, United States
• University of Chicago Medical Center — Chicago, Illinois, United States
• University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
• University of Kansas Medical Center — Kansas City, Kansas, United States
• University of Kentucky Chandler Medical Center — Lexington, Kentucky, United States
• Jewish Hospital Louisville — Louisville, Kentucky, United States
• Tulane University Hospital and Clinic — New Orleans, Louisiana, United States
• Ochsner Clinic — New Orleans, Louisiana, United States
• New England Medical Center — Boston, Massachusetts, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• Lahey Clinic — Burlington, Massachusetts, United States
• Mayo Clinic Arizona — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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