Botox for Non-surgical Lateral Release in Patellofemoral Pain

Stopped early · Phase 3 · Has a placebo group

Conditions studied: Patellofemoral Pain Syndrome

In brief

The purpose of this study is to determine whether the use of botulinum toxin A injected into the lateral thigh muscle improves knee function and reduces knee pain secondary to patellofemoral syndrome. The study hypothesis is that botulinum toxin + specific exercises will be superior to specific exercises alone in improving knee function and reducing knee pain in individuals with patellofemoral syndrome.

Key facts

Study ID

NCT00496964

Run by

Virginia Commonwealth University

People needed

5

Starts

2005-05-01

Expected to finish

2008-06-01

Last updated by the study team

2017-10-23

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• retropatellar knee pain
• pain with two of: prolonged sitting, climbing stairs, squatting, running, kneeling, hopping, jumping
• pain with patellar palpation
• symptoms minimum 1 month
• Visual Analog Scale for pain (VAS) usual pain 4 of 10 on VAS [0-10 scale, anchors 0 = no pain, 10 = worst pain imaginable]

You may not qualify if…

• history knee surgery
• history patellar dislocation
• clinical evidence of meniscal lesion, ligamentous instability, traction apophysitis around the patellofemoral complex, patellar tendon pathology, chondral damage, osteoarthrosis, spinal referred pain

Where it is running

• Virginia Commonwealth University — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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