HSV-2 Shedding Resolution After Acyclovir Treatment

Completed

Conditions studied: Genital Herpes

In brief

The purpose of the study is to evaluate the pattern of viral shedding after beginning treatment with acyclovir for a clinical recurrence of genital herpes and to compare it with the pattern of viral shedding during an untreated clinical recurrence of genital herpes.

Key facts

Study ID

NCT00495573

Run by

University of Washington

People needed

36

Starts

2007-06-01

Expected to finish

2012-03-01

Last updated by the study team

2012-03-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• History of clinically-evident genital herpes
• 3 or more clinical genital herpes recurrences within the prior 12 months
• HSV-2 seropositive by HSV Western Blot
• Willing and able to comply with study protocol

You may not qualify if…

• Pregnancy
• Taking daily antiviral therapy for genital herpes
• HIV seropositive or known immunocompromising medical condition
• Plan to move from the Seattle area within the next year
• Hypersensitivity to or intolerance of acyclovir

Where it is running

• University of Washington Virology Research Clinic — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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