High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer

Completed · Phase 3

Conditions studied: Prostate Cancer

In brief

Objective: The objective of this study is test the hypothesis that delivering a higher percentage of the radiation dose as external radiation versus implant will lead to higher tumor control rates. Research design A total of 600 patients with AJC clinical stage T1-T2 prostatic carcinoma (Gleason grade 7 to 10 and/or PSA 10 to 20 ng/ml) will be randomized to treatment with 44 Gy versus 20 Gy external radiation plus a Pd-103 implant boost (90 Gy versus 105 Gy, respectively).

Key facts

Study ID

NCT00494546

Run by

VA Puget Sound Health Care System

People needed

568

Starts

1999-01-01

Expected to finish

2007-06-01

Last updated by the study team

2007-06-29

Who can join

Age: 40 and older, up to 80. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Males
• Prostate cancer
• PSA 10-20
• Gleason score 7-10

You may not qualify if…

• Lymph nodes positive

Where it is running

• VA Puget Sound — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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