Combination Therapy in Patients With Depression

Completed · Phase 4 · Has a placebo group

Conditions studied: Depressive Symptoms

In brief

The purpose of the study is to compare sertraline and atomoxetine/sertraline combination therapy in patients with persistent depressive symptoms.

Key facts

Study ID: NCT00485862
Run by: Eli Lilly and Company
People needed: 214
Starts: 2003-06-01
Expected to finish: 2005-01-01
Last updated by the study team: 2007-06-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Meet DSM-IV criteria for major depression with a HAMD-17 rating scale score of at least 18 at visit 1
Adult men or women, 18 years of age or older
Must be able to swallow capsules
Laboratory results must show no clinically significant abnormalities
If suicidal ideation is present, the investigator should assess its severity and the potential need for other interventions and determine whether these are compatible with study participation

You may not qualify if…

Have a documented history of Bipolar I or II disorder, or of psychosis.
Have a history of any seizure disorder (other than febrile seizures) or patients who have taken (or are currently taking) anticonvulsants for seizure control.
Have a history of ADHD
Have a history of severe allergies to more than 1 class of medications or multiple adverse drug reactions
Are currently using alcohol, drugs of abuse, or any prescribed or over-the-counter medication in a manner which the investigator considers indicative of abuse

Where it is running

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559), Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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