The OMEGA Study: Use of Eye Drops to Treat Geographic Atrophy Associated With Age-Related Macular Degeneration (Dry AMD)

Status unconfirmed · Phase 2 · Has a placebo group

Conditions studied: Age-Related Macular Degeneration

In brief

The purpose of this trial is to compare the ability of two doses of OT-551 ophthalmic solution and drug-free solution to safely and effectively treat geographic atrophy associated with age-related macular degeneration.

Key facts

Study ID

NCT00485394

Run by

Othera Pharmaceuticals

People needed

198

Starts

2007-06-01

Last updated by the study team

2008-04-02

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• have a clinical diagnosis of GA in one or both eyes;
• be of non-childbearing potential

You may not qualify if…

• have GA secondary to any condition other than AMD in the study eye;
• have a BCVA of 20/200 or worse in the non-study eye;
• have a history of or current choroidal neovascularization in either eye, or the need for any study eye anti-angiogenic therapy;
• have any ocular condition in the study eye that would progress during the course of the study and could affect central vision or other ocular conditions that may be a confounding factor in this study;
• need to wear contact lenses in the study eye during the study;
• had confounding ocular surgery in the study eye;
• have concomitant treatment with any systemic or ocular medication that is known to be toxic to the lens, retina, or optic nerve;

Where it is running

• Study site — Mesa, Arizona, United States
• Study site — Tucson, Arizona, United States
• Study site — Beverly Hills, California, United States
• Study site — Oxnard, California, United States
• Study site — Sacramento, California, United States
• Study site — Denver, Colorado, United States
• Study site — Boynton Beach, Florida, United States
• Study site — Miami, Florida, United States
• Study site — Indianapolis, Indiana, United States
• Study site — Novi, Michigan, United States
• Study site — New York, New York, United States
• Study site — Charlotte, North Carolina, United States
• Study site — Cleveland, Ohio, United States
• Study site — Lakewood, Ohio, United States
• Study site — Portland, Oregon, United States
• Study site — Dallas, Texas, United States
• Study site — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.