Analysis of Aldehyde Biomarkers of Exposure and Host Response

Stopped early · Not applicable

Conditions studied: Smoking Cessation

In brief

Analysis of aldeyde biomarkers of exposure and host response The purpose of this prospective, open-label, clinical trial is to establish the feasibility and validity of exhaled breath condensate (EBC) biomarkers for use in studies designed to evaluate harm reduction strategies of smoking. This will be accomplished by measuring selected markers in EBC believed related to the pathogenesis of lung disease before and after a smoking cessation intervention.

Key facts

Study ID

NCT00482690

Run by

University of Nebraska

People needed

35

Starts

2005-08-23

Expected to finish

2007-09-09

Last updated by the study team

2023-09-07

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Smokers of at least 5 pack years;
• Stable smoking habit for 3 months;
• Willing to make a serious quit attempt;
• Able to use nicotine replacement therapy

You may not qualify if…

• Regular use of anti-inflammatory medication
• Inflammatory lung disease
• Unstable medical condition

Where it is running

• Unversity of Nebraska Medical Center — Omaha, Nebraska, United States

Full record on ClinicalTrials.gov

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