Treating Depression With Transcranial Direct Current Stimulation (tDCS)

Completed · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Depression

In brief

The purpose of this study is to see if transcranial direct current stimulation may improve the symptoms of depression.

Key facts

Study ID

NCT00481988

Run by

New York State Psychiatric Institute

People needed

20

Starts

2007-03-01

Expected to finish

2011-01-01

Last updated by the study team

2013-05-20

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Has a diagnosis of a major depressive episode or bipolar disorder and is currently in a major depressive episode (without psychotic features)
• Total pretreatment HDRS (Hamilton Depression Rating Scale)-24 score >= 18 (The Hamilton Depression Rating Scale is an interviewer scored tool for assessing the severity of depressive symtoms. The scale ranges from 0 (no symptoms, absence of depression) to 64
• Category Ham-24 Score Normal, not depressed 9 or less Mildly depressed 10 to 19 Moderately depressed 20 to 29 Markedly/severely depressed 30 or more)
• Capable and willing to provide informed consent

You may not qualify if…

• History of depression previously untreated with medication, bipolar disorder, schizophrenia, schizoaffective disorder (non mood disorder), psychosis, depression secondary to a medical condition, mental retardation, substance dependence or abuse within the past year (except nicotine), psychotic features in this or previous episodes, amnestic disorder, dementia or mms<24, DELIRIUM
• Significant current history of autoimmune, endocrine, viral or vascular disorder affecting the brain
• History of unstable cardiac disease, uncontrolled hypertension, or sleep apnea
• Changes in psychotropic medications within two weeks prior to study entry or patient is unable to maintain stable doses throughout the study trial
• Subject has an active suicidal plan and/or attempted suicide in the past twelve months
• Patients with a CGI of 6 or greater
• Subject is pregnant or has a positive pregnancy serum test

Where it is running

• New York State Psychiatric Institute — New York, New York, United States

Full record on ClinicalTrials.gov

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