The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture

Stopped early

Conditions studied: Breast Cancer

In brief

The objective of the present study is to determine whether or not primary human mammary epithelial cells are competent for use in molecular studies of transepithelial electrophysiology focusing on the function of the tight junction protein claudin 3. Human breast Tissue will be removed from mastectomy specimens and used as a source to generate epithelial cells for study.

Key facts

Study ID

NCT00481585

Run by

Hackensack Meridian Health

People needed

13

Starts

2007-05-01

Last updated by the study team

2014-02-04

Who can join

Age: any. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Subjects of this pilot study are limited to those female patients who are undergoing therapeutic or prophylactic mastectomy procedures conducted by the department of Surgery at HUMC.

You may not qualify if…

• From within this population, no exclusion criteria shall be applied based on age, race, ethnicity, gender, HIV status, or menopause.

Where it is running

• Hackensack Univeristy Medical Center — Hackensack, New Jersey, United States

Full record on ClinicalTrials.gov

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