Dose Response Study of a Topical Formulation of Nitroglycerin for the Treatment of Raynaud's Phenomenon

Completed · Phase 2

Conditions studied: Raynaud's Disease

In brief

The purpose of this clinical study is to determine the response to two different dosage strengths of a topical nitroglycerin gel in patients with Raynaud's Phenomenon. Patient fingers will be monitored for changes in blood flow and skin temperature. Symptoms of pain, tingling and numbness will also be monitored.

Key facts

Study ID

NCT00480753

Run by

MediQuest Therapeutics

People needed

15

Starts

2007-05-01

Expected to finish

2007-08-01

Last updated by the study team

2007-12-24

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with Raynaud's phenomenon
• Patients who are willing to discontinue any current therapies for Raynaud's phenomenon

You may not qualify if…

• The use of any medication containing nitroglycerin or known to interact with nitroglycerin
• Patients with a history of migraine or other severe headaches
• Open skin lesions or skin conditions in the area where medication is to be applied
• Pregnant or nursing women or those wishing to become pregnant.

Where it is running

• The Center for Rheumatology — Albany, New York, United States

Full record on ClinicalTrials.gov

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