Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major

Completed

Conditions studied: Thalassemia Major

In brief

The purpose of this study is to collect peripheral blood and bone marrow aspirate samples from thalassemia patients in Tehran, in a collaborative effort to develop an erythroid lineage specific chimerism assay applicable to patients with thalassemia. Development of such an assay would be useful both for identification of the exact mutation causing the disease, as well as for providing a direct method to measure and monitor the kinetics of donor erythropoiesis in this patient population following transplant.

Key facts

Study ID

NCT00480506

Run by

Dana-Farber Cancer Institute

People needed

40

Starts

2004-04-01

Expected to finish

2005-10-01

Last updated by the study team

2012-02-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Thalassemia patients being treated at Shariati Hospital in Tehran.

Where it is running

• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Tehran University of Medical Sciences — Tehran, Iran

Full record on ClinicalTrials.gov

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