Sweetened Beverages and Food Intake

Completed · Not applicable

Conditions studied: Overweight, Obesity

In brief

The purpose of this study is to investigate whether beverages sweetened with fructose promote overconsumption of calories as compared to beverages sweetened with glucose or a non-caloric sweetener.

Key facts

Study ID

NCT00475475

Run by

University of Washington

People needed

10

Starts

2007-05-01

Expected to finish

2011-12-01

Last updated by the study team

2012-05-02

Who can join

Age: 18 and older, up to 25. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age: 18-25 years
• Body mass index: 20-25 kg/m2
• Weight stable to within 5 pounds for 6 months prior to entering the study
• Within 10 pounds of their lifetime maximum weight
• Ability to be admitted for 5 hours to the General Clinical Research Center of the University of Washington on three occasions
• Ability to provide informed written consent
• Willingness to consume only food provided by the Nutrition Research Kitchen of the University of Washington General Clinical Research Center for three periods of 8 days each

You may not qualify if…

• History of cardiovascular disease
• Presence of diabetes mellitus or impaired glucose tolerance (fasting glucose > 100 mg/dL)
• Presence of hypertension (blood pressure systolic/diastolic higher than 140/90)
• Presence of phenylketonuria
• Presence of fructose malabsorption or hereditary fructose intolerance
• Presence of another chronic or psychiatric illness
• Use of anabolic steroids, glucocorticoids, warfarin, beta-blockers, antidepressants, or lipid-lowering agents
• Use of antibiotic drugs within 3 months of enrollment into the study
• Use of tobacco products
• Pregnancy or female subject not using contraception
• Regular intense exercise (> 3 hour per week)
• Vegetarian or extreme dietary preferences
• Alcohol consumption of more than 2 drinks per day
• Presence of eating disorder
• History of frequent attempts at weight loss
• Currently dieting or in a weight control program
• Recent blood donation or enrolled in other research which requires blood sampling
• Presence or history of anemia

Where it is running

• University of Washington General Clinical Research Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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