The Montefiore Metoclopramide Study

Completed · Phase 4 · Has a placebo group

Conditions studied: Nausea, Extrapyramidal Symptoms

In brief

Metoclopramide is a dopamine antagonist frequently used for the treatment of nausea, vomiting, and migraine headaches in Emergency Departments. However, little research has focused on the optimal dose of metoclopramide for treatment of nausea in the emergency department. We propose a randomized, double-blind, placebo controlled trial to investigate the optimal dose of metoclopramide for treatment of nausea.

Key facts

Study ID

NCT00475306

Run by

Montefiore Medical Center

People needed

289

Starts

2007-05-01

Expected to finish

2008-02-01

Last updated by the study team

2012-12-31

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• primary or secondary complaints of nausea/vomiting
• age 21-65

You may not qualify if…

• pregnancy
• use of anti-histamine or dopamine antagonist as outpatient and/or within last 24 hours of presentation
• previous adverse reaction to study medications
• use of opioid medications prior to study start time within that ED visit

Where it is running

• Montefiore Medical Center — The Bronx, New York, United States

Full record on ClinicalTrials.gov

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