Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)

Completed

Conditions studied: Clubfoot

In brief

The goal of this study is to identify and characterize the genetic loci causing idiopathic talipes equinovarus (clubfoot). The hypothesis is that a few genes account for a substantial fraction of ITEV and that these genes can be identified in defined populations. Towards this goal, in preliminary studies, Dr. Hecht's group has identified two genes, NAT2 and CASP10, which demonstrate evidence for linkage and association to ITEV.

Key facts

Study ID

NCT00474344

Run by

University of British Columbia

People needed

370

Starts

2004-08-01

Expected to finish

2013-08-01

Last updated by the study team

2022-05-18

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• One family member, usually child, must have clubfoot

Where it is running

• University of Texas — Houston, Texas, United States
• BC Children's Hospital — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

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