Effect of S-adenosylmethionine (SAMe) on Blood Levels of Homocysteine

Completed · Phase 1 · Has a placebo group

Conditions studied: Hyperhomocysteinemia

In brief

The purpose of this study is to investigate whether S-adenosylmethionine (SAMe), a natural substance available as a nutritional supplement, can influence blood levels of homocysteine (Hcy). More specifically, we will determine if chronic oral SAMe administration affects homocysteine metabolism in patients with vascular disease who have mild to moderate hyperhomocysteinemia.

Key facts

Study ID

NCT00473200

Run by

Baylor Research Institute

People needed

27

Starts

2009-08-01

Expected to finish

2013-07-01

Last updated by the study team

2018-03-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age and older
• Must have a serum homocysteine value greater than or equal to 14 μmol/L
• Stable weight 3 months prior to study participation

You may not qualify if…

• Subjects with a BMI greater than 35 or less than 18
• Currently taking B 100 or other high-dose B vitamin supplements within the past 12 months
• Taken methionine or SAMe supplements within the past 3 months

Where it is running

• Baylor University Medical Center — Dallas, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.