Low Dose Apomorphine and Parkinsonism

Withdrawn before enrolling · Phase 2

Conditions studied: Parkinson's Disease

In brief

The purpose of this study is to determine if low doses of apomorphine worsen the motor symptoms of Parkinson's disease.

Key facts

Study ID

NCT00472355

Run by

Oregon Health and Science University

People needed

0

Starts

2005-10-01

Expected to finish

2007-05-01

Last updated by the study team

2018-11-29

Who can join

Age: 35 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have idiopathic Parkinson's disease treated with levodopa and experiencing motor fluctuations
• Response to levodopa had to be documented by a 10 percent increase in finger or foot tapping speed

You may not qualify if…

• Clinically significant cardiovascular, cerebrovascular, hepatic and renal diseases
• Psychosis
• Allergy to apomorphine or 5ht3 inhibitors
• Prolonged qt interval
• Pregnancy/breast-feeding
• Hemodynamic instability
• Severe nausea
• Alcohol/drug abuse
• Other unstable medical conditions

Where it is running

• Department of Neurology, Oregon Health and Science University, Mail Code OP32, 3181 SW Sam Jackson Park Road — Portland, Oregon, United States

Full record on ClinicalTrials.gov

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