Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

Stopped early

Conditions studied: Brain and Central Nervous System Tumors, Thrombocytopenia

In brief

RATIONALE: Studying samples of blood in the laboratory from patients receiving temozolomide may help doctors learn how temozolomide works in the body. It may also help doctors learn more about how a patient's genes may affect the risk of developing thrombocytopenia. PURPOSE: This clinical trial is studying the pharmacokinetics in patients with newly diagnosed high-grade glioma receiving temozolomide and radiation therapy.

Key facts

Study ID
NCT00471653
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
People needed
10
Starts
2006-11-11
Expected to finish
2009-08-18
Last updated by the study team
2018-07-09

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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