Study Of Gemcitabine Plus AG-013736 Versus Gemcitabine For Advanced Pancreatic Cancer.

Completed · Phase 3 · Has a placebo group

Conditions studied: Carcinoma, Pancreatic Ductal

In brief

The purpose of this study is to determine whether investigational study drug, AG-013736, and gemcitabine are effective in the first-line treatment of advanced pancreatic cancer.

Key facts

Study ID

NCT00471146

Run by

Pfizer

People needed

630

Starts

2007-07-01

Expected to finish

2010-11-01

Last updated by the study team

2012-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Histologically or cytologically confirmed, metastatic or locally-, advanced pancreatic adenocarcinoma not amenable to curative resection.
• Adequate renal, hepatic and bone marrow function.
• Performance status 0 or 1.

You may not qualify if…

• Prior treatment with any systemic chemotherapy for metastatic disease.
• Prior treatment with gemcitabine, AG-013736, or other vascular endothelial growth factor inhibitors.
• Current or recent bleeding, thromboembolic event and or use of a thrombolytic agent.
• Inability to take oral medication.

Where it is running

• Pfizer Investigational Site — Pleasent Hill, California, United States
• Pfizer Investigational Site — Pomona, California, United States
• Pfizer Investigational Site — Pomona, California, United States
• Pfizer Investigational Site — Rancho Cucamonga, California, United States
• Pfizer Investigational Site — Rancho Mirage, California, United States
• Pfizer Investigational Site — Redlands, California, United States
• Pfizer Investigational Site — San Diego, California, United States
• Pfizer Investigational Site — San Diego, California, United States
• Pfizer Investigational Site — San Leandro, California, United States
• Pfizer Investigational Site — West Covina, California, United States
• Pfizer Investigational Site — Hollywood, Florida, United States
• Pfizer Investigational Site — Pembroke Pines, Florida, United States
• Pfizer Investigational Site — Stuart, Florida, United States
• Pfizer Investigational Site — Tampa, Florida, United States
• Pfizer Investigational Site — Atlanta, Georgia, United States
• Pfizer Investigational Site — Augusta, Georgia, United States
• Pfizer Investigational Site — Augusta, Georgia, United States
• Pfizer Investigational Site — Coeur d'Alene, Idaho, United States
• Pfizer Investigational Site — Alton, Illinois, United States
• Pfizer Investigational Site — Chicago, Illinois, United States
• Pfizer Investigational Site — Beech Grove, Indiana, United States
• Pfizer Investigational Site — Indianapolis, Indiana, United States
• Pfizer Investigational Site — Indianapolis, Indiana, United States
• Pfizer Investigational Site — Jeffersonville, Indiana, United States
• Pfizer Investigational Site — Pasadena, California, United States

Full record on ClinicalTrials.gov

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