Optimizing Image Quality in Obese Patients Undergoing Coronary Computed Tomography (CT) Angiography

Completed

Conditions studied: Coronary Angiography, Obesity, Coronary Disease

In brief

The purpose of this cardiovascular imaging research is to look at ways to improve the way we can look at the pictures of the heart. Patients undergo CT scans of the heart for a variety of reasons, including symptoms and/or tests suggestive of coronary artery disease (chest pain, shortness of breath, abnormal stress test, follow up exam of known/existing coronary disease, abnormal calcium score, etc.) This study involves finding ways to optimize quality of the scan in persons of size. This is because in patients with a BMI (body mass index) of greater than 40, it is usually difficult to "see" all the arteries around the heart satisfactorily. Body mass index is a number that we can get by putting your height and weight in a formula. The purpose of this study is to use a new computer software program to help us interpret your heart study.

Key facts

Study ID

NCT00468195

Run by

Corewell Health East

People needed

175

Starts

2007-05-01

Expected to finish

2010-09-01

Last updated by the study team

2012-03-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body Mass Index greater than 35
• Age greater than 18 years
• Ability to provide informed consent
• Scheduled to undergo coronary CTA -

You may not qualify if…

• Presence of pre-existing CAD (prior myocardial infarction, prior angiographic evidence of significant coronary artery disease, prior coronary bypass surgery).
• Renal insufficiency (creatinine ≥1.6) or renal failure requiring dialysis.
• Inability or refusal to provide informed consent.
• Pregnancy or unknown pregnancy status.
• Age less than 18 years.
• Patients with known allergy to iodinated contrast.
• Computed tomography imaging, or contrast administration, within the past 48 hours.
• Known asthma or reactive airway disease.

Where it is running

• William Beaumont Hospital — Royal Oak, Michigan, United States

Full record on ClinicalTrials.gov

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