Effect of Daily Calorie or Alternate-day Calorie Reductions on Risk for Cardiovascular Disease and Cancer

Completed · Not applicable

Conditions studied: Moderately Overweight Individuals

In brief

The purpose of this study is to examine and compare the effects of alternate-day reductions in calorie intake or daily calorie restriction on the risk for cardiovascular disease and cancer.

Key facts

Study ID

NCT00467220

Run by

University of California, San Francisco

People needed

24

Starts

2007-04-01

Expected to finish

2015-12-17

Last updated by the study team

2020-01-22

Who can join

Age: 35 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and female; body mass index (BMI) between 20-30 kg/m2;
• Age between 35-65 years; sedentary (light exercise less than 1h per week) or moderately active (1 to 2h per week);
• Weight stable for >3 months prior to the beginning of the study;
• Able to give written informed consent;
• Female subjects must be post-menopausal for at least 2 years and can not be on hormone replacement therapy (HRT).

You may not qualify if…

• Diabetic;
• History of cardiovascular disease, i.e. myocardial infarction or stroke;
• History of cancer;
• Taking glucose lowering medication;
• Taking weight loss medication

Where it is running

• San Francisco General Hospital — San Francisco, California, United States

Full record on ClinicalTrials.gov

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