Measuring Blood Flow in the Brain
Completed
Conditions studied: Traumatic Brain Injury, Healthy
In brief
This study will test a method of measuring brain blood flow called near infrared spectroscopy (NIRS). It will determine whether NIRS gives the same results as the more commonly used technique, functional magnetic resonance imaging (fMRI). Healthy normal volunteers between 18 and 60 years of age may be eligible for this study. Participants come to the NIH up to six times for experiments using NIRS and fMRI. They do the following tasks while they are undergoing NIRS or fMRI: * looking at a computer monitor while a checkerboard pattern changes * wiggling the toes and moving the fingers * Reading words on a computer screen and pushing one button if they are plants and another if they are animals. For NIRS, a frame is placed on the head and held it in place with a metal band. The frame holds sensors that contact the scalp. For fMRI, the subject lies on a table that can slide in and out of an MRI scanner, a metal cylinder surrounded by a strong magnetic field. fMRI uses a strong magnetic field and radio waves to obtain images of the brain while the subject performs tasks. During the procedure, The subject wears earplugs to muffle the sound of loud knocking noises that occur during scanning.
Key facts
- Study ID
- NCT00466934
- Run by
- National Institute of Neurological Disorders and Stroke (NINDS)
- People needed
- 31
- Starts
- 2007-04-24
- Expected to finish
- 2011-12-29
- Last updated by the study team
- 2017-07-02
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Pregnancy.
- History of hypertension.
- History of any disease of the central nervous system.
- Current use of sedating medication, including antihistamines.
- Subjects with any of the following will be excluded from MRI testing: aneurysm clip; implanted neural stimulator; implanted cardiac pacemaker or auto-defibrillator; cochlear implant; ocular foreign body, such as metal shavings; permanent eyeliner; insulin pump; or irremovable body piercing due to the possible dangerous effects of the MRI magnet upon metal objects in the body.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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