Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients

Completed

Conditions studied: Heart Transplant

In brief

Injury of transplant tissue by a transplant recipient's immune system continues to be the leading cause of graft rejection and recipient death. The purpose of this study is to identify a single test or a combination of noninvasive tests currently used for heart transplant monitoring that correlate to long-term graft survival.

Key facts

Study ID

NCT00466804

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

263

Starts

2007-06-01

Expected to finish

2011-07-01

Last updated by the study team

2016-01-01

Who can join

Age: 10 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age greater than 10 and a body mass of 30 kg (66 lbs) or more
• On waiting list for a heart transplant for whom a donor heart available
• Willing to comply with study protocol
• Willing to use acceptable forms of contraception
• Parent or guardian willing to provide consent, if applicable

You may not qualify if…

• Receiving multiple organ transplants
• Previously received organ transplants
• Other comorbidities that, in the opinion of the site investigator, would interfere with the study
• Currently taking immunosuppression for nontransplant reasons
• Participation in an interventional clinical trial
• Pregnancy or breastfeeding

Where it is running

• University of California — San Francisco, California, United States
• Northwestern University Medical School — Chicago, Illinois, United States
• Loyola University School of Medicine — Maywood, Illinois, United States
• University of Maryland — Baltimore, Maryland, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Beth Israel Medical Center — Newark, New Jersey, United States
• Mount Sinai School of Medicine — New York, New York, United States
• The Cleveland Clinic Foundation — Cleveland, Ohio, United States
• Medical City Dallas Hospital — Dallas, Texas, United States
• University of Utah, LDS Hospital — Salt Lake City, Utah, United States
• University of Utah, VACM.LDS — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.