Multicenter Orthopaedics Outcomes Network for ACL Reconstructions

Running, not enrolling

Conditions studied: Rupture of Anterior Cruciate Ligament

In brief

The purpose of this study is to determine the effect of modifiable risk factors on knee function, osteoarthritis, and re-rupture of the anterior cruciate ligament (ACL) following ACL reconstruction.

Key facts

Study ID

NCT00463099

Run by

Vanderbilt University Medical Center

People needed

3294

Starts

2002-01-01

Expected to finish

2028-12-01

Last updated by the study team

2026-01-27

Who can join

Age: 10 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All ACL-deficient candidates scheduled for a unilateral ACL reconstruction at one of the participating MOON sites.

You may not qualify if…

• Persons undergoing a simultaneous bilateral ACL reconstruction
• Patients less than 10 years old and older than 80 years old
• Patients unwilling or unable to complete their follow-up questionnaire

Where it is running

• University of Colorado — Boulder, Colorado, United States
• University of Iowa — Iowa City, Iowa, United States
• Washington University at St. Louis — St Louis, Missouri, United States
• Hospital for Special Surgery — New York, New York, United States
• Duke University — Durham, North Carolina, United States
• Cleveland Clinic — Cleveland, Ohio, United States
• The Ohio State University — Columbus, Ohio, United States
• Vanderbilt University Medical Center — Nashville, Tennessee, United States

Full record on ClinicalTrials.gov

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