Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Leukemia

Completed · Phase 1

Conditions studied: Leukemia

In brief

RATIONALE: Drugs used in chemotherapy, such as clofarabine, topotecan, vinorelbine, thiotepa, and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects and best dose of clofarabine when given together with topotecan, vinorelbine, thiotepa, and dexamethasone in treating young patients with relapsed or refractory acute leukemia.

Key facts

Study ID
NCT00462787
Run by
Memorial Sloan Kettering Cancer Center
People needed
23
Starts
2007-04-01
Expected to finish
2013-11-01
Last updated by the study team
2013-11-14

Who can join

Age: any, up to 28. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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